Thermo Fisher Scientific ADAMTS4 Polyclonal Antibody
ADAMTS4 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot에 최적화되어 있으며, 인간 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었고, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
- Western Blot (WB): 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the propeptide domain of human ADAMTS4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2222313 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the ADAMTS protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif. Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The enzyme encoded by this gene lacks a C-terminal TS motif and is responsible for the degradation of aggrecan (a major proteoglycan of cartilage) and brevican (a brain-specific extracellular matrix protein). The cleavage of these substrates suggests key roles in arthritic disease and in the central nervous system, potentially in the progression of glioma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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