Thermo Fisher Scientific CDK5 Monoclonal Antibody (1H3)
CDK5 단백질을 인식하는 Mouse IgG1 단클론 항체로 인간, 마우스, 랫트 반응성. Western blot 및 IHC(F) 검증 완료. 내인성 28 kDa CDK5에 특이적이며 p35/p25와 교차 반응 없음. 단백질 G 정제, 액상 형태, -20°C 보관.
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Thermo Fisher Scientific CDK5 Monoclonal Antibody (1H3)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50–1:1,000 |
| Immunohistochemistry (Frozen) (IHC(F)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H3 |
| Immunogen | Purified rat Cdk5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 10 mM HEPES, pH 7.5, with 100 µg/mL BSA, 50% glycerol, 150 mM NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942667 |
Product Specific Information
Specific for endogenous levels of the ~28 kDa Cdk5 protein.
Shows no cross-reactivity with the Cdk5 cofactor p35 or its degradation product p25.
Target Information
CDK5 is a member of the Cyclin-Dependent Kinase family, most abundant in the mammalian brain.
The active form of CDK5, also known as neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein derived from a 35 kDa neuron-specific precursor, essential for CDK5 kinase activity.
CDK5 plays a crucial role in neuronal migration during CNS development and phosphorylates various substrates involved in cellular processes such as adhesion, motility, synaptic plasticity, and drug addiction.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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