Thermo Fisher Scientific GNAT1 Polyclonal Antibody
GNAT1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC(F)에서 사용 가능. 인간과 생쥐에 반응하며, 항원 친화 크로마토그래피로 정제됨. 시각 신호전달 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 37–350 of Human GNAT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.34 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545812 |
Product Specific Information
- Recommended positive controls: NT2D1, IMR32, U87-MG, mouse eye
- Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (92%), Xenopus laevis (92%), Dog (99%), Chicken (96%), Bovine (98%), Guinea pig (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) that stimulates coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses.
The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods and is also expressed in other cells, implicated in bitter taste transduction in rat taste cells.
Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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