Thermo Fisher Scientific MRGD Polyclonal Antibody
Human MRGPRD 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며 1 mg/mL 농도의 액상 형태. 통증 감각 조절 관련 연구에 적합하며, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 9.3 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 2nd extracellular domain of human MRGPRD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551310 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human (100%), Gorilla, Gibbon, Monkey (94%).
Target Information
May regulate nociceptor function and/or development, including the sensation or modulation of pain.
Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evokes Ca(2+) influx in cells expressing the receptor.
Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting coupling with G-protein G(q) and G(i).
Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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