Thermo Fisher Scientific MMP13 Polyclonal Antibody
MMP13 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 사용 가능. 높은 종간 반응성(인간, 말, 돼지 등)과 항원 친화 크로마토그래피 정제. 장기 보관 시 -20°C에서 안정적.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 15–25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Horse, Human, Non-human primate, Pig, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from internal region of human MMP13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551308 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Horse, Rabbit, Pig (100%)
Mouse, Rat, Sheep, Dog, Hamster (94%)
Target Information
MMP13 (collagenase 3) is involved in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN.
It cleaves triple helical collagens (types I, II, III) with highest activity on soluble type II collagen, and can degrade collagen types IV, XIV, and X.
MMP13 plays roles in wound healing, tissue remodeling, cartilage degradation, bone development, mineralization, and ossification.
It is essential for normal embryonic bone development and ossification.
Mutations can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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