Thermo Fisher Scientific CD82 Monoclonal Antibody (C33)
CD82 단백질을 인식하는 C33 클론의 mouse monoclonal antibody로 다양한 응용(WB, IHC, ICC, Flow, IP)에 사용 가능. Human 시료 반응성, Protein A 정제, 1 mg/mL 농도, 4°C 보관. 암 전이 억제 관련 CD82 연구에 적합.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
| Flow Cytometry (Flow) | 1–4 µg/mL |
| Immunoprecipitation (IP) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C33 |
| Immunogen | C91/PL (human HTLV-1+ T cell line) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745531 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Target Information
CD82 is a metastasis suppressor gene product and a member of the transmembrane 4 superfamily. Expression of this gene is downregulated during tumor progression in human cancers and can be activated by p53 through a consensus binding sequence in its promoter. Expression of CD82 and p53 are strongly correlated, and loss of both is associated with poor survival in prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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