Thermo Fisher Scientific CD82 Monoclonal Antibody (C33), Biotin
CD82 단백질을 인식하는 Biotin 결합 마우스 단일클론 항체. Western blot, IHC, ICC, Flow cytometry, IP 등 다양한 응용에 적합. 인간 시료 반응성. 액상 형태, 4°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1–12 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C33 |
| Immunogen | C91/PL (human HTLV-1+ T cell line) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| RRID | AB_2745527 |
Available Formats
Product Specific Information
This antibody recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Target Information
This metastasis suppressor gene product is a membrane glycoprotein that belongs to the transmembrane 4 superfamily. Expression of this gene is downregulated during tumor progression in human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Expression of CD82 and p53 are strongly correlated, and loss of both is associated with poor survival in prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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