Thermo Fisher Scientific CD82 Monoclonal Antibody (C33), PE
CD82 단백질을 인식하는 Mouse IgG2a 단클론 항체로, PE 형광체가 결합된 제품입니다. 인간 시료에 반응하며 Flow Cytometry에 적합합니다. 암 전이 억제 관련 연구 및 세포 표면 단백질 분석에 유용합니다.
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Thermo Fisher Scientific CD82 Monoclonal Antibody (C33), PE
Applications
- Flow Cytometry (Flow)
Tested Dilution: 10 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C33 |
| Immunogen | C91/PL (human HTLV-1⁺ T cell line) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745530 |
Additional Formats
- Unconjugated (MA5-28572)
- APC (MA5-28567)
- Biotin (MA5-28568)
- FITC (MA5-28569)
- Request custom conjugation available
Product Specific Information
This antibody recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Recommended dilution is for 100 µL of whole blood or 1×10⁶ cells in suspension.
Target Information
CD82 is a metastasis suppressor membrane glycoprotein belonging to the transmembrane 4 superfamily. Expression of this gene is downregulated in tumor progression and can be activated by p53 through a consensus promoter binding sequence. Expression of CD82 and p53 is strongly correlated, and loss of both is associated with poor survival in prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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