Thermo Fisher Scientific CD82 Monoclonal Antibody (C33)
CD82 단백질을 인식하는 Mouse IgG2a 단일클론 항체(C33)로, 인간 시료에 반응합니다. WB, IHC, ICC, Flow Cytometry 등 다양한 응용에 사용 가능하며, 액상 형태로 제공됩니다. Protein A 정제, PBS 버퍼에 보존제로 없이 4°C 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
| Flow Cytometry (Flow) | 1–4 µg/mL |
| Immunoprecipitation (IP) | Assay-Dependent |
| Functional Assay | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C33 |
| Immunogen | C91/PL (human HTLV-1+ T cell line) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745529 |
Available Conjugated Formats
Product Specific Information
This antibody recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Functional Application: Inhibition.
Target Information
CD82 is a metastasis suppressor gene product and a membrane glycoprotein belonging to the transmembrane 4 superfamily. Expression of this gene is downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in its promoter. Expression of CD82 and p53 are strongly correlated, and loss of both proteins is associated with poor survival in prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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