Thermo Fisher Scientific C1orf57 Polyclonal Antibody
C1orf57 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS(40% glycerol) 용액 형태로 제공되며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NTPCR. Recombinant protein control fragment (Product #RP-103184) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791344 |
Product Specific Information
Immunogen sequence:
PVDGFYTEEV RQGGRRIGFD VVTLSGTRGP LSRVGLEPPP GKRECRVGQY VVDLTSFEQL ALPV
Target Information
C1orf57 (also known as nucleoside triphosphate phosphohydrolase) belongs to the THEP1 NTPase family. It and its mouse homolog, 2310079N02Rik, are 190 amino acid proteins exhibiting nucleotide phosphatase activity towards ATP, GTP, TTP, CTP, and UTP. Acting as a monomer, it also hydrolyzes nucleoside diphosphates with lower efficiency.
The gene encoding C1orf57 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and comprising approximately 8% of the human genome. Chromosome 1 contains around 3,000 genes, many of which are associated with various diseases. Notably, Hutchinson-Gilford progeria is linked to the LMNA gene, which encodes lamin A. Defects in LMNA can cause nuclear abnormalities and accelerated aging. Other chromosome 1–associated conditions include familial adenomatous polyposis (MUTYH gene), Stickler syndrome, Parkinson’s disease, Gaucher disease, and Usher syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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