Thermo Fisher Scientific p27 Kip1 Monoclonal Antibody (3D8)
인간 CDKN1B(p27 Kip1)를 검출하는 Mouse IgG1 단클론 항체로, ELISA 및 Western blot에 적합합니다. 세포주기 조절 연구에 활용되며, 22kDa 단백질을 인식합니다. 비결합형 액상 형태로 4°C 단기, -20°C 장기 보관 가능합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D8 |
| Immunogen | Purified recombinant fragment of human CDKN1B expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10989811 |
Product Specific Information
MA5-15635 targets CDKN1B in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human CDKN1B expressed in E. coli.
MA5-15635 detects CDKN1B, which has a predicted molecular weight of approximately 22 kDa.
Target Information
p27 Kip1 functions as a negative regulator of G1 phase progression and may mediate TGF-β–induced G1 arrest. It is an important regulator of cell cycle progression and a potent inhibitor of cyclin E- and cyclin A-CDK2 complexes.
p27 Kip1 forms complexes with cyclin D-CDK4 and contributes to assembly, stability, and activation modulation of CCND1-CDK4 complexes. Depending on its phosphorylation state and stoichiometry, p27 Kip1 can act as either an inhibitor or activator of cyclin D-CDK4 complexes.
This protein has a molecular weight of approximately 27 kDa, and its degradation—triggered by CDK-dependent phosphorylation and ubiquitination via SCF complexes—is required for the transition from cellular quiescence to a proliferative state.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific JAK2 Monoclonal Antibody (1C1)
742,900원
Thermo Fisher Scientific
Thermo Fisher Scientific VCAM-1 Monoclonal Antibody (6G9)
742,900원
Thermo Fisher Scientific
Thermo Fisher Scientific p27 Kip1 Monoclonal Antibody (3D8)
678,400원
Thermo Fisher Scientific
Thermo Fisher Scientific CD19 Monoclonal Antibody (2E2)
739,000원
Thermo Fisher Scientific
Thermo Fisher Scientific CDK1 Monoclonal Antibody (8C5A7F10)
678,400원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|