Thermo Fisher Scientific CDK1 Monoclonal Antibody (8C5A7F10)
CDK1 단백질을 인식하는 mouse monoclonal antibody로 인간 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry, ELISA에 사용 가능하며, 비결합형 액상 형태입니다. 세포주기 조절 연구 및 CDK1 관련 신호전달 분석에 적합합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CDK1 Monoclonal Antibody (8C5A7F10)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8C5A7F10 |
| Immunogen | Purified recombinant fragment of CDC2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10986110 |
Product Specific Information
MA5-15631 targets CDC2 in indirect ELISA, FACS, IF, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of CDC2 expressed in E. coli.
MA5-15631 detects CDC2, which has a predicted molecular weight of approximately 34 kDa.
Target Information
CDK1 (Cell Division Control protein 1) is essential for the completion of START, the controlling event in the cell cycle required to initiate mitosis.
It acts as the catalytic subunit of the M-Phase Promoting Factor (MPF), a universal eukaryotic protein kinase complex that induces entry into mitosis.
Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays apoptosis onset.
Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.