Thermo Fisher Scientific ROS1 Polyclonal Antibody
Human ROS1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 glycerol로 안정화되어 있습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA583949
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ROS1. Recombinant protein control fragment (Product #RP-101100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791101 |
Product Specific Information
Immunogen sequence:
WKYNEFYHVK TSCSQGPAYV CNITNLQPYT SYNVRVVVVY KTGENSTSLP ESFKTKAGVP NKPGIPKLLE GSKNSIQWEK AEDNGC
Target Information
ROS1 is a tyrosine kinase that functions as a growth or differentiation factor receptor. Protein kinases transfer a phosphate group from ATP to substrate proteins, mediating most signal transduction in eukaryotic cells. They regulate cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
The protein kinase family includes over 500 gene products and is divided into 8 major groups based on sequence comparison of catalytic domains. The tyrosine kinase group primarily regulates cell-cell interactions such as differentiation, adhesion, motility, and death. Approximately 90 TK genes have been sequenced — 58 receptor TKs (EGFR, EPH, FGFR, PDGFR, TRK, VEGFR families) and 32 cytosolic TKs (ABL, FAK, JAK, SRC families).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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