Thermo Fisher Scientific DOK3 Monoclonal Antibody (OTI1H9)
Human DOK3 단백질(aa 63–317)을 항원으로 제작된 Mouse IgG1 단클론 항체. Western blot에 적합하며, carrier-free 형태로 제공되어 결합 실험에 활용 가능. Lyophilized 형태, PBS+8% trehalose buffer, -20°C 보관.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 63–317 of human DOK3 (NP_079148) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
To use this carrier-free antibody for conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
DOK3 proteins are enzymatically inert adaptor or scaffolding molecules that provide a docking platform for multimolecular signaling complex assembly.
DOK3 acts as a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1, and may modulate ABL1 function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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