Thermo Fisher Scientific MRPL24 Monoclonal Antibody (OTI1B4)
MRPL24 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat에 반응하며, IgG2b 아이소타입을 가진 Mouse 유래 항체입니다. 동결건조 형태로 제공되며, 1 mg/mL 농도에서 PBS(8% 트레할로스) 완충액에 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 9-216 of human MRPL24 (NP_078816) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- 재구성 시, 멸균 증류수 100 µL를 첨가하여 최종 항체 농도를 약 1 mg/mL로 맞추는 것을 권장합니다.
- 결합 실험용으로 carrier-free 항체를 사용할 경우, 추가적인 탈염 과정을 수행하는 것이 좋습니다.
(예: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882)
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and function in mitochondrial protein synthesis.
Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition—opposite to that of prokaryotic ribosomes.
Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA.
The proteins composing the mitoribosome vary significantly among species, making sequence homology recognition difficult.
This gene encodes a 39S subunit protein more than twice the size of its E. coli counterpart. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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