
Thermo Fisher Scientific ZFAND1 Polyclonal Antibody
Human ZFAND1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:30~1:150 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:30–1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length fusion protein of human ZFAND1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636621 |
Product Specific Information
This antibody detects endogenous levels of total ZFAND1 protein.
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, often involving transcriptional activation or repression. Most zinc-finger proteins possess a Kruppel-type DNA-binding domain and a KRAB domain, which interacts with KAP1 to recruit histone-modifying proteins.
ZFAND1 (AN1-type zinc finger protein 1) is a 268-amino-acid protein containing two AN1-type zinc fingers. These domains are typically found in proteins with ubiquitin-like domains and are involved in the ubiquitination pathway. AN1-type zinc fingers have six conserved cysteines and two histidines forming a zinc-bound alpha/beta fold. Two isoforms of ZFAND1 are produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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