Thermo Fisher Scientific FMO5 Polyclonal Antibody
Thermo Fisher Scientific의 FMO5 폴리클로날 항체로 인간 및 마우스 시료에 반응합니다. Western blot과 IHC(파라핀)에서 사용 가능하며 고순도 항원 친화 크로마토그래피로 정제되었습니다. 내인성 FMO5 단백질 검출에 적합합니다.
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human FMO5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636633 |
Product Specific Information
This antibody detects endogenous levels of total FMO5 protein.
Target Information
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in humans, resulting in a small subpopulation with reduced TMA N-oxidation capacity (fish odor syndrome, trimethylaminuria).
Three forms of the enzyme—FMO1 (fetal liver), FMO2 (adult liver), and FMO3—are encoded by genes clustered in the 1q23–q25 region.
Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyze oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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