Thermo Fisher Scientific BAG1 Monoclonal Antibody (2D3)
BAG1 단백질을 인식하는 Mouse 모노클론 항체로 Western blot과 ELISA에 적합. Human, Mouse, Rat 반응성. Unconjugated 형태, ascites buffer에 보관. 항세포사멸 경로 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D3 |
| Immunogen | BAG1 (NP_004314, 241–345 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
EKIADQLEEL NKELTGIQQG FLPKDLQAEA LCKLDRRVKA TIEQFMKILE EIDTLILPEN FKDSRLKRKG LVKKVQAFLA ECDTVEQNIC QETERLQSTN FALAE
Target Information
The oncogene BCL2 is a membrane protein that blocks a step in the pathway leading to apoptosis (programmed cell death).
The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene (BAG1).
It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.
At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site and alternative downstream AUG translation initiation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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