Thermo Fisher Scientific Human TIP60 Synthetic Peptide
Human TIP60 단백질의 카복시 말단 15개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. Western blot 차단 실험에 사용 가능하며, PA5-34548 항체와 함께 적용됩니다. 고순도 액상 형태로 제공되며 연구용으로만 사용됩니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 15 amino acid sequence near the carboxy terminus of human KAT5.
PEP-1591 can be used as a blocking peptide with polyclonal antibody PA5-34548.
For use as a blocking peptide in Western blot, incubate the peptide with an equal volume of antibody for 30 minutes at 37ºC.
Target Information
TIP60 is a transcription factor originally isolated as an HIV-1 TAT-interactive protein. It interacts with the viral TAT protein, leading to HTATIP polyubiquitination and degradation.
Belonging to the MYST family of histone acetyltransferases (HATs), TIP60 acts as a catalytic subunit of the NuA4 complex, which acetylates histones H4 and H2A to activate transcription.
TIP60 serves as a co-regulator of transcription factors and may either promote or suppress tumorigenesis. It is involved in DNA repair, apoptosis, and signal transduction processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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