Thermo Fisher Scientific SERCA2 ATPase Polyclonal Antibody
Rabbit polyclonal antibody against SERCA2 ATPase for WB, IHC, and ICC applications. Reacts with human, mouse, and rat. Lyophilized form purified by antigen affinity chromatography. Reconstitute to 500 µg/mL; store at -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human SERCA2 ATPase (665–679aa, QRDACLNARCFARVE) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745952 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
SERCA2 ATPase is one of the SERCA Ca(2+)-ATPases located in the sarcoplasmic or endoplasmic reticulum of muscle cells. It catalyzes ATP hydrolysis coupled with calcium translocation from the cytosol to the sarcoplasmic reticulum lumen, regulating muscle contraction and relaxation. Mutations in this gene cause Darier-White disease (keratosis follicularis), an autosomal dominant skin disorder characterized by loss of cell adhesion and abnormal keratinization. Alternative splicing results in multiple isoforms.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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