Thermo Fisher Scientific NBN Monoclonal Antibody (OTI1C9), TrueMAB

Thermo Fisher Scientific NBN Monoclonal Antibody (OTI1C9), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000
Publications: -

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The p95 gene (identical to NBS1 and nibrin) is part of the hMre11/hRad50 double-strand break complex. This complex is implicated in Nijmegen breakage syndrome, an autosomal recessive disorder characterized by increased cancer incidence, cell cycle checkpoint defects, and ionizing radiation sensitivity. This reveals a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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