Thermo Fisher Scientific NMDAR2A Polyclonal Antibody
Thermo Fisher Scientific의 NMDAR2A Polyclonal Antibody는 NR2A 단백질을 특이적으로 검출하는 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. 인간, 마우스, 토끼, 랫트 반응성이 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 4 publications |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
| Immunoprecipitation (IP) | 3 µL/200 µg lysate | View 3 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rabbit, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein from the C-terminal region of the NR2A subunit of rat GRIN2A |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Affinity chromatography |
| Storage Buffer | 5 mM Ammonium bicarbonate, pH 7.5 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2112313 |
Product Specific Information
- In Western blot, this antibody detects a single ~180 kDa protein representing NR2A in rat brain homogenate.
- It shows no cross-reactivity with NR2B.
- Reconstitute with 50 µL of PBS before use.
Target Information
N-methyl-D-aspartate (NMDA) receptors are ionotropic glutamate-gated ion channels involved in long-term potentiation, a key mechanism underlying memory and learning.
NMDA receptor channels are heteromers composed of the NMDAR1 (GRIN1) subunit and one or more of the NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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