Thermo Fisher Scientific TPT1 Polyclonal Antibody
TPT1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 형태, -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TPT1 (Accession P13693), corresponding to amino acid residues E80–K130 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850528 |
Product Specific Information
Antibody detects endogenous levels of total TCTP.
Target Information
TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium-binding proteins.
It is localized in the cytoplasm and widely expressed, serving as a transcriptional activator, calcium transporter, histamine inducer, and antiapoptotic caspase-3 inhibitor.
TPT1 acts as a cytokine-like molecule that triggers the release of histamine, IL-4, and IL-13 from basophils, as well as IL-8 secretion and calcium response in eosinophils.
It plays a pivotal role in allergic diseases and is implicated in neurodegenerative disorders such as Alzheimer’s disease and Down syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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