Thermo Fisher Scientific UBF-1 Polyclonal Antibody
UBF-1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF에 사용 가능하며 인간, 마우스, 랫트 반응성. 액상 형태로 1 mg/mL 농도, -20°C 보관. 리보솜 RNA 전사 및 크로마틴 리모델링 연구에 적합.
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Thermo Fisher Scientific UBF-1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human UBTF (Accession P17480), corresponding to amino acid residues E516–E566 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850530 |
Product Specific Information
Antibody detects endogenous levels of total UBF1.
Target Information
UBF-1 encodes a member of the HMG-box DNA-binding protein family.
This protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions.
It may also be involved in chromatin remodeling and pre-rRNA processing, with activity regulated by phosphorylation and acetylation.
Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Pseudogenes are located on the short arm of chromosomes 3, 11, and X, and the long arm of chromosome 11.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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