Thermo Fisher Scientific Phospho-AS160 (Ser588) Recombinant Rabbit Monoclonal Antibody (5H9L9)
Phospho-AS160 (Ser588)을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 Immunocytochemistry에 적합. 높은 특이성과 민감도, 로트 간 일관성 제공. 단백질 A로 정제된 액상 항체로, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5H9L9 |
| Immunogen | Peptide corresponding to human Phospho-AS160 (Ser588) (aa583–aa592) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2692252 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, and Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to the larger rabbit immune repertoire
Target Information
AS160 (TBC1D4) is a GTPase-activating protein for RAB2A, RAB8A, RAB10, and RAB14. The isoform 2 of this protein promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, increasing glucose uptake. Mutations in this gene are associated with Diabetes mellitus, non-insulin-dependent, type 5 (NIDDM5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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