Thermo Fisher Scientific FLT4 Monoclonal Antibody (OTI1G7), TrueMAB
FLT4 단일클론 항체(OTI1G7)는 인간 VEGFR-3 단백질을 표적으로 하는 TrueMAB 형 항체로, Western blot에 최적화되어 있습니다. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공되며 연구용으로 혈관 및 림프관 발달 관련 연구에 적합합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1063–1363 of human FLT4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Vascular endothelial growth factor (VEGF) is a key regulator of blood vessel development during embryogenesis and angiogenesis in adult tissues.
VEGFC, a related factor, specifically stimulates lymphatic vessel growth through its receptor VEGFR-3 (FLT4).
Inactivation of the VEGFR-3 gene in mice leads to defective vascular organization and cardiovascular failure during early embryonic development, highlighting its essential role in embryonic cardiovascular formation prior to lymphatic vessel emergence.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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