Thermo Fisher Scientific N2DL4 Monoclonal Antibody (205001)

Applications

Flow Cytometry (Flow)

• Tested Dilution: 2.5 µg per million cells

Neutralization (Neu)

• Tested Dilution: Assay-Dependent

Product Specifications

Product Specific Information

• In direct ELISAs, no cross-reactivity with recombinant mouse Rae-1 alpha, beta, gamma, or gamma is observed.
• By flow cytometry, no cross-reactivity with mouse Rae-1 alpha or mouse Rae-1 gamma has been observed.
• Reconstitute at 0.5 mg/mL in sterile PBS.
• Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

This gene belongs to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3.
This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences.
This protein functions as a ligand for the NKG2D receptor, expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
[provided by RefSeq, Aug 2011]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.