Thermo Fisher Scientific IL17B Monoclonal Antibody (174113)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Flow Cytometry (Flow)

2.5 µg per million cells

-

ELISA (ELISA)

0.5-2 µg/mL (Detection), 2-8 µg/mL (Capture)

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

174113

Immunogen

E. coli-derived recombinant human IL-17B Gln21-Phe180 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL17B,uniProtId:Q9UHF5-1,ncbiNodeId:9606,antigenRange:21-180,antigenLength:180,antigenImageFileName:MA5-23886_IL17B_Q9UHF5-1_House_mouse.svg,antigenImageFileNamePDP:MA5-23886_IL17B_Q9UHF5-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2576704

Product Specific Information

In Western blots, approximately 25% cross-reactivity with recombinant mouse IL-17B is observed and no cross-reactivity with recombinant human (rh) IL-17, rhIL-17C, rhIL-17E or rhIL-17F is observed. In sandwich ELISAs, less than 0.5% cross-reactivity with rmIL-17B, and no cross-reactivity with rhIL-17C, rhIL-17D, rhIL-17E, rhIL-17F, or rhIL-17 is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.