Thermo Fisher Scientific MAL Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat, Xenopus

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptides corresponding to residues C(114)F D G F T Y (R/K) H Y H E N I(126) of human MAL. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAL,uniProtId:P21145-1,ncbiNodeId:9606,antigenRange:114-126,antigenLength:153,antigenImageFileName:PA1-085_MAL_P21145-1_Rabbit.svg,antigenImageFileNamePDP:PA1-085_MAL_P21145-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2139001

Product Specific Information

PA1-085 detects MAL from rat, mouse, xenopus and human samples.

PA1-085 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~ 17 kDa protein corresponding to MAL from rat kidney extracts.

The PA1-085 immunogen is a synthetic peptides corresponding to residues C(114)F D G F T Y (R/K) H Y H E N I(126) of human MAL. This peptide (Cat. # PEP-249) can be used in neutralization and control experiments.

Target Information

MAL, a nonglycosylated integral membrane proteolipid, has been identified as a major internal component of glycolipid-enriched membrane (GEM) microdomains. MAL is the first integral membrane proteolipid component to have been shown as a necessary element in the cellular apical sorting apparatus for newly synthesized proteins. In its steady state this highly hydrophobic proteolipid, resides predominantly in the apical zone of polarized epithelial cells. It has also been shown in itinerant protein cycling between the plasma membrane and endosomes and in other cells. This 17-kDa proteolipid contains four putative transmembrane domains. These domains along with its protein trafficking properties are defined by the specific signals delegated by its specific amino acid sequence.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.