Thermo Fisher Scientific Pseudorabies Virus Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1.0 µg/mL

View 2 publications 2 publications

Immunohistochemistry (IHC)

-

View 6 publications 6 publications

Immunohistochemistry (Frozen) (IHC (F))

1.0 µg/mL

-

Immunohistochemistry - Free Floating (IHC (Free))

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

-

View 2 publications 2 publications

Product Specifications

Species Reactivity

Virus

Published species

Virus

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Purified pseudorabies virus-Bartha.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_325805

Product Specific Information

PA1-081 detects pseudorabies virus (PRV).

PA1-081 has been successfully used in Western blot and immunohistochemistry procedures. By Western blot, this antibody detects proteins in the range of 80-115 kDa representing various PRV proteins. Immunohistochemical staining of PRV in rat hypothalamus from animals injected with PRV into the vitreous body of the eye results in intense staining of neurons in the superchiasmatic nucleus.

The PA1-081 immunogen is purified PRV-Bartha.

Target Information

Herpes simplex virus (HSV), varicella-zoster virus (VZV) and pseudorabies virus (PRV) comprise a family of neurotropic viruses known as alphaherpesviruses. PRV is primarily a disease of swine which serve as a reservoir for the virus and the principal source of natural infection for a diverse range of secondary hosts, including cattle, sheep, goats, dogs, cats, and many feral species. Humans and apes are refractory to PRV infection. PRV infects the epithelium of the host where it then spreads to axons of the peripheral nervous system (PNS). The virus opportunistically avails itself of the neuronal retrograde transport pathway which can facilitate transfer to the brain. This unique aspect of PRV allows it to be used as a powerful research tool to study neural connectivity and trace neuronal circuitry in the peripheral (PNS) and central nervous system (CNS).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.