Thermo Fisher Scientific PHYHD1 Polyclonal Antibody
Western blot과 Immunocytochemistry에 적합한 Rabbit Polyclonal Antibody. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상. PBS/glycerol buffer에 보관되며 연구용으로 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PHYHD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720895 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
PHYHD1 (phytanoyl-CoA dioxygenase domain containing 1) is a 291 amino acid protein belonging to the PHYH family and PHYHD1 subfamily. Encoded by a gene located on human chromosome 9q34.11, PHYHD1 exists as three alternatively spliced isoforms and functions as an alpha-ketoglutarate-dependent dioxygenase. It participates in metal ion binding and oxidoreductase activity, acting on single donors with incorporation of two atoms of oxygen. Related to PHYH (phytanoyl-CoA 2-hydroxylase), an Fe(II) and 2-oxoglutarate (2OG)-dependent oxygenase, PHYHD1 shows homologues across metazoans and bacteria. It may also play a role in DNA methylation during early postnatal liver development and mammalian differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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