Thermo Fisher Scientific MYBPC3 Polyclonal Antibody
MYBPC3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ELISA에 적합. 마우스 및 랫트 반응성. Affinity Chromatography로 정제된 액상 항체로, -20°C 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 200–400 of human MYBPC3 (NP_0002472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.29 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804948 |
Product Specific Information
Immunogen sequence:
SSKVGQHLQL HDSYDRASKV YLFELHITDA QPAFTGSYRC EVSTKDKFDC SNFNLTVHEA MGTGDLDLLS AFRRTSLAGG GRRISDSHED TGILDFSSLL KKRDSFRTPR DSKLEAPAEE DVWEILRQAP PSEYERIAFQ YGVTDLRGML KRLKGMRRDE KKSTAFQKKL EPAYQVSKGH KIRLTVELAD HDAEVKWLKN G
Positive Samples: Rat heart
Target Information
Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle A bands. It binds MHC, F-actin, and native thin filaments, modifying the activity of actin-activated myosin ATPase. It may modulate muscle contraction or play a structural role. Mutations in MYBPC3 are associated with cardiomyopathies such as familial hypertrophic cardiomyopathy, dilated cardiomyopathy, and left ventricular non-compaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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