Thermo Fisher Scientific Phospho-SOX2 (Ser83) Polyclonal Antibody
인간 SOX2 단백질의 Ser83 인산화 부위를 인식하는 폴리클로날 항체입니다. Rabbit IgG로 제작되었으며, 단백질 A 및 항원 친화 크로마토그래피로 정제되었습니다. 세포 신호전달 및 줄기세포 연구용으로 적합하며, 4°C 단기 보관 또는 -20°C 장기 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Dot blot (DB) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S83 of human SOX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2195776 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in embryonic development and cell fate determination. The SOX2 protein is essential for stem-cell maintenance in the central nervous system and regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). SOX2 may act as a transcriptional activator by forming complexes with other proteins. Mutations in SOX2 are associated with bilateral anophthalmia, optic nerve hypoplasia, and syndromic microphthalmia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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