Thermo Fisher Scientific LGP2 Polyclonal Antibody
LGP2 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 항바이러스 선천면역 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
- Suggested positive control: Rat kidney tissue lysate
- Blocking peptide: PEP-0552
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 11 amino acid peptide from near the center of human LGP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 2–8°C (up to 3 months); -20°C (long-term) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153756 |
Target Information
Anti-viral innate immune responses are triggered by pathogen-associated molecular patterns, such as intracellular nucleic acids resulting from viral infections. These responses represent the first line of defense against infectious organisms. Toll-like receptors (TLR3, 7, 8, 9) detect foreign nucleic acids as transmembrane pattern recognition receptors in immune cells.
RIG-I and MDA5, members of the CARD-helicase family, perform similar roles in the cytoplasm. LGP2 is structurally related to RIG-I and MDA5 but lacks a CARD domain, suggesting it functions as a negative-feedback regulator in intracellular antiviral signaling. At least four isoforms of LGP2 have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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