Thermo Fisher Scientific EYA4 Polyclonal Antibody

Applications

Tested Application

• Western Blot (WB): 1:500–1:3,000

Product Specifications

Product Specific Information

• Keep as concentrated solution.
• Predicted reactivity: Chicken (91%).
• Positive Control: A431, HeLa.
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity and may be important for eye development and function of the mature organ of Corti.
Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss (DFNA10).
The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack.
Defects in this gene are also associated with dilated cardiomyopathy 1J.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.