Thermo Fisher Scientific Phospho-EIF2S1 (Ser51) Polyclonal Antibody
Phospho-EIF2S1 (Ser51) 특이적 폴리클로날 항체로, Western blot 및 ELISA에 적합. 인간 및 랫트 반응성, Rabbit IgG 기반. 스트레스 반응 관련 단백질 EIF2S1 인산화 상태 검출에 유용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S51 of human EIF2S1 (NP_0040851) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.7275 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914844 |
Product Specific Information
- Positive test controls include: HeLa, C6
- Localization: Cytoplasmic granule
- Immunogen sequence: SELSR
Target Information
EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-121272_EIF2S1_P05198-1_Rabbit.svg, PA5-121272_EIF2S1_P05198-1_Rabbit_PDP.jpeg)
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