Thermo Fisher Scientific Cytokeratin 7 Monoclonal Antibody (OV-TL12/30)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse

Class

Monoclonal

Type

Antibody

Clone

OV-TL12/30

Immunogen

OTN11 human ovarian carcinoma cells. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytokeratin 7,uniProtId:P08729-1,ncbiNodeId:9606,antigenRange:1-469,antigenLength:469,antigenImageFileName:18-0234_Cytokeratin_7_P08729-1_House_mouse.svg,antigenImageFileNamePDP:18-0234_Cytokeratin_7_P08729-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.03755 mg/mL

Purification

purified

Storage buffer

PBS with 1% BSA

Contains

0.1% sodium azide

Storage conditions

2-8°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2925244

Product Specific Information

The 54 kDa protein, cytokeratin 7, is found in most glandular and transitional epithelia. It has detected cytokeratin 7 in a large number of epithelial cell types, including many ductal and glandular epithelia by immunohistochemistry of paraffin-embedded tissue. Primarily, cytokeratin 7 antibody does not react with stratified squamous epithelia but is reactive with transitional epithelium of the urinary tract. Positive tissue: Pancreas/bladder cancer. This antibody is specific for cytokeratin 7, and does not exhibit cross-reactivity with other filament types, including vimentin, desmin, glial fibrillary acidic protein and neurofilament protein.

Expected Staining Pattern: Cytoplasmic

Target Information

Cytokeratin 7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.