Thermo Fisher Scientific FGFR4 Recombinant Rabbit Monoclonal Antibody (124)
Rat FGFR4/CD334 단백질을 특이적으로 인식하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체. ELISA에 적합하며 높은 특이성과 일관된 로트 간 품질을 제공. 보존제 무첨가, 단기 4°C 및 장기 -20°C 보관 권장.
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- MA531295
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- pk
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Applications
- ELISA (ELISA)
Tested Dilution: 1:250–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 124 |
| Immunogen | Recombinant Rat FGFR4/CD334 Protein (Met1–Asp367) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786932 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody shows specificity for Rat FGFR4/CD334.
Target Information
FGFR4 is a member of the FGFR family of receptor tyrosine kinases, which regulate various cellular functions including:
- Angiogenesis
- Mitogenesis
- Osteogenesis
- Myogenesis
- Carcinogenesis
- Cellular differentiation
- Tissue repair after injury
FGFR family members are implicated in diseases such as cancer, rheumatoid arthritis, and diabetic retinopathy.
FGFR4 is required for normal down-regulation of CYP7A1 expression, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. It also plays roles in postnatal lung development and skeletal muscle cell lineage formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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