Thermo Fisher Scientific FCAR Recombinant Rabbit Monoclonal Antibody (013)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

This antibody has specificity for Rat CD89/FCAR.

Target Information

This gene encodes a receptor for the Fc region of IgA and belongs to the immunoglobulin gene superfamily. The receptor is a transmembrane glycoprotein found on myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils. It mediates immunologic responses to pathogens by interacting with IgA-opsonized targets and triggering defense mechanisms including:

• Phagocytosis
• Antibody-dependent cell-mediated cytotoxicity
• Release of inflammatory mediators

Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.