Thermo Fisher Scientific GPR3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

10 µg/mL

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GPR3. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR3,uniProtId:P46089-1,ncbiNodeId:9606,antigenRange:1,antigenLength:330,antigenImageFileName:PA5-32852_GPR3_P46089-1_Rabbit.svg,antigenImageFileNamePDP:PA5-32852_GPR3_P46089-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550314

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Horse (94%); Bovine, Rabbit (88%); Elephant, Panda, Pig (82%).

For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1, 000 members and is the largest known class of molecular targets with proven therapeutic value. GPR3 is an orphan receptor with constitutive G signaling activity. GPR3 modulates a number of brain functions, including behavioral responses to stress, neurite outgrowth and amyloid-beta peptide generation suggesting that it may play a role in Alzheimer`s disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.