Thermo Fisher Scientific GPR153 Polyclonal Antibody
Rabbit polyclonal antibody against human GPR153. Validated for IHC(P) and ELISA. High specificity and affinity purified. Suitable for detecting GPR153 in human and primate tissues. For research use only.
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- PA532849
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) [IHC(P)] | 34 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminal cytoplasmic domain of human GPR153 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550311 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Monkey (100%); Rat (94%); Marmoset, Mouse, Bovine, Hamster, Elephant (88%); Bat, Dog, Pig (81%). - For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors or 7TM receptors, are a superfamily of proteins involved in various stimulus-response pathways.
They translate extracellular signals into intracellular signals via G protein activation and respond to signaling molecules such as hormones and neurotransmitters.
GPR153 (G protein-coupled receptor 153), also known as PGR1, is a 609 amino acid multi-pass membrane protein functioning as an orphan receptor in the GPR1 family.
The GPR153 gene maps to human chromosome 1, which spans approximately 260 million base pairs, contains over 3,000 genes, and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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