Thermo Fisher Scientific GPR153 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

34 µg/mL

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 16 amino acid peptide from C-terminal cytoplasmic domain of human GPR153. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR153,uniProtId:Q6NV75-1,ncbiNodeId:9606,antigenRange:609,antigenLength:609,antigenImageFileName:PA5-32849_GPR153_Q6NV75-1_Rabbit.svg,antigenImageFileNamePDP:PA5-32849_GPR153_Q6NV75-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550311

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Monkey (100%); Rat (94%); Marmoset, Mouse, Bovine, Hamster, Elephant (88%); Bat, Dog, Pig (81%).

For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR153 (G protein-coupled receptor 153), also known as PGR1, is a 609 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR1 family. The gene encoding GPR153 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.