Thermo Fisher Scientific GPRC5B Polyclonal Antibody
Rabbit polyclonal antibody targeting human GPRC5B C-terminal peptide. Suitable for IHC and ELISA. Reacts with multiple species including human, dog, and pig. High specificity and purity via antigen affinity chromatography. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–10 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Horse, Human, Non-human primate, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-terminal cytoplasmic domain of human GPRC5B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550316 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Orangutan, Monkey, Marmoset, Dog, Bovine, Elephant, Panda, Horse, Pig (100%);
Gibbon, Opossum, Turkey, Chicken (94%); Xenopus (89%); Rat (83%).
For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were treated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
This gene encodes a member of the type 3 G protein-coupled receptor family, characterized by a 7-transmembrane domain motif. The encoded protein may modulate insulin secretion, and increased expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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