Thermo Fisher Scientific Insulin (beta-Cell and Insulinoma Marker) Monoclonal Antibody (SPM139)
베타세포 및 인슐린종 마커로 사용되는 단클론 항체로, 인간·돼지·소 인슐린에 반응합니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용이 가능하며, 단백질 A/G로 정제된 액상 형태입니다. 4°C에서 보관하며 Mouse 및 Rat에는 반응하지 않습니다.
- 카탈로그번호
- 3630-MSM1X-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Insulin (beta-Cell and Insulinoma Marker) Monoclonal Antibody (SPM139)
Thermo Fisher Scientific Insulin (beta-Cell and Insulinoma Marker) Monoclonal Antibody (SPM139)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM139 |
| Immunogen | Full length (1–84 amino acid) purified pig insulin conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Mouse or Rat
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. Insulin promotes glycogen storage, triglyceride formation, and synthesis of proteins and nucleic acids.
It is a 51-amino acid polypeptide derived from proinsulin, which is cleaved into A and B chains linked by disulfide bonds and one molecule of C-peptide.
Insulin deficiency leads to diabetes mellitus, a major cause of morbidity and mortality. Insulin is also found in tumors of β-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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