Thermo Fisher Scientific Insulin (beta-Cell and Insulinoma Marker) Monoclonal Antibody (SPM139)
베타세포 및 인슐린종 마커로 사용되는 단클론 항체. 다양한 종(Bovine, Human, Pig)에 반응하며, IHC, ICC, Flow Cytometry 등 다중 응용 가능. 단백질 A/G 정제, 보존제 무첨가 PBS 용액 형태로 제공. 연구용으로만 사용.
- 카탈로그번호
- 3630MSM1XP1ABX
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM139 |
| Immunogen | Full length (1–84 amino acid) purified pig insulin conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
- Does not react with Mouse or Rat.
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, triglyceride formation, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide produced from the precursor peptide proinsulin, which is post-translationally cleaved into two chains (A and B) linked by disulfide bonds and one molecule of C-peptide.
Insulin deficiency results in diabetes mellitus, a major cause of morbidity and mortality. It is also present in tumors of β-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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