Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (rIRDN/8546)
인슐린 및 인슐린종 세포 마커 검출용 마우스 단클론 항체. 인간 인슐린 단백질에 특이적이며 IHC(P) 및 IHC(PFA) 적용 가능. 고순도 Protein A/G 정제, 200 µg/mL 농도, 연구용 전용 시약.
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Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (rIRDN/8546)
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunohistochemistry (PFA fixed) (IHC (PFA)): 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rIRDN/8546 |
| Immunogen | Recombinant full-length human Insulin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It promotes glycogen storage, triglyceride formation, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide produced from proinsulin, which is post-translationally cleaved into peptide A and peptide B chains linked by disulfide bonds along with one molecule of C-peptide.
Deficiency of insulin results in diabetes mellitus, a major cause of morbidity and mortality. Insulin is also present in tumors of beta-cell origin, such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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