Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (rIRDN/8546)
인슐린 및 인슐린종 마커로 사용되는 단클론 항체로, 인간 인슐린 단백질에 특이적 반응. IHC(P) 및 IHC(PFA) 적용 가능. 고순도 Protein A/G 정제, 액상 형태로 제공. 연구용 전용 시약으로 안정적 저장 및 운송 가능.
- 카탈로그번호
- 3630MSM15P1ABX
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rIRDN/8546 |
| Immunogen | Recombinant full-length human Insulin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide produced from proinsulin, which is post-translationally cleaved into two chains (peptide A and peptide B) linked by disulfide bonds and one molecule of C-peptide.
Deficiency of insulin results in diabetes mellitus. Insulin is also present in tumors of β-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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