Thermo Fisher Scientific PSMA1 Recombinant Rabbit Monoclonal Antibody (JB89-30)
Thermo Fisher Scientific의 PSMA1 Recombinant Rabbit Monoclonal Antibody (JB89-30)은 인간 PSMA1 단백질을 타겟으로 하는 재조합 단클론 항체입니다. Western blot, IHC, Flow cytometry에 적합하며 Protein A로 정제된 고순도 항체로, 안정적 저장이 가능합니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB89-30 |
| Immunogen | Synthetic peptide within Human Proteasome 20S C2 (aa 214–263) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848604 |
Product Specific Information
Positive Control:
Rat testis tissue, human liver cancer tissue, human pancreas tissue, mouse cerebellum tissue, K562, PC-3M, mouse testis tissue lysate, mouse colon tissue lysate.
Target Information
Proteolytic degradation is critical to maintaining appropriate levels of short-lived and regulatory proteins involved in cellular metabolism, stress response, antigen presentation, receptor modulation, ion channels, cell cycle regulation, transcription, and signaling.
The ubiquitin-proteasome pathway deconstructs most proteins in the cytosol and nucleus of eukaryotic cells, while others are degraded via the vacuolar pathway (endosomes, lysosomes, endoplasmic reticulum).
The 26S proteasome is an ATP-dependent, multisubunit (~31 subunits), barrel-shaped molecular complex (~2.5 MDa). It consists of a 20S proteolytic core and one or two 19S regulatory subunits that recognize ubiquitinated proteins, unfold them, and translocate them into the 20S lumen.
Defects in the ubiquitin-proteasome pathway are linked to several genetic diseases, including cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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