Thermo Fisher Scientific GSS Recombinant Rabbit Monoclonal Antibody (JB95-33)
Glutathione Synthetase(GSS)를 인식하는 재조합 래빗 모노클로날 항체로 다양한 응용(WB, IHC, ICC, Flow)에 사용 가능. HEK293 발현 시스템 기반, Protein A 정제, 고순도 액상 형태. 연구용으로 산화 스트레스 및 세포 보호 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB95-33 |
| Immunogen | Recombinant protein within Human Glutathione Synthetase (aa 301–420) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848606 |
Product Specific Information
Positive Control Samples:
SiHa, mouse colon tissue, rat liver tissue lysate, rat epididymis tissue, human tonsil tissue, human colon cancer tissue, human kidney tissue, HepG2, LOVO.
Target Information
Glutathione plays a crucial role in cellular protection against oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport.
The GSS protein functions as a homodimer catalyzing the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione, the second step in glutathione biosynthesis.
Defects in the GSS gene may cause glutathione synthetase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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