Thermo Fisher Scientific VCAM-1 Monoclonal Antibody (1.4C3)
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CD106(VCAM-1)을 표적하는 Mouse Monoclonal Antibody로, IHC(P/F), ICC/IF 등 다양한 응용에 적합. Human 및 Mouse 시료에 반응하며, Protein A/G 정제 및 PBS 버퍼에 보존. 염증성 질환 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (IHC) | - | View 10 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:12.5–1:25 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:12.5–1:25 | - |
| Immunocytochemistry (ICC/IF) | 1:10–1:100 | View 2 publications |
| Flow Cytometry (Flow) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1.4C3 |
| Immunogen | Stimulated human umbilical vein endothelial cells (HUVEC) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979792 |
Product Specific Information
- MA5-11447 targets CD106 in IHC (P, F) and ICC/IF applications and shows reactivity with Human samples.
- The immunogen used is stimulated human umbilical vein endothelial cells (HUVEC).
- Successfully used in immunohistochemistry analysis of VCAM1 in mouse E16.5 frozen lung sections.
Target Information
VCAM-1 is a cell surface sialoglycoprotein expressed by cytokine-activated endothelium.
It regulates leukocyte migration, leukocyte-endothelial adhesion, and signal transduction, and may play a role in various inflammatory diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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