Thermo Fisher Scientific ABCA5 Polyclonal Antibody
ABCA5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 사용 가능하며, 합성 펩타이드(aa 450–550)를 면역원으로 제작. Lyophilized 형태로 제공되며, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous (PubMed)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 450–550 of human ABCA5 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: ABCA5.
Target Information
ABCA5 (ATP-binding cassette, sub-family A (ABC1), member 5) is a 1,642 amino acid protein belonging to the ABC transporter superfamily and the ABCA family.
The ABC1 subfamily is exclusive to multicellular eukaryotes.
ABCA5 is ubiquitously expressed, with high levels in testis, skeletal muscle, kidney, liver, and placenta.
It is a multi-pass membrane protein containing two ABC transporter domains and exists as three alternatively spliced isoforms.
ABCA5 may play a role in processing autolysosomes and is linked to lysosomal diseases, tumor development, and cardiomyocyte and follicular cell activities.
It may serve as a specific urine marker for diagnosis of patients with high-grade prostatic intraepithelial neoplasia (HGPIN).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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